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Cytokine and chemokine quantification. Cytokine and chemokine levels were compared between treatment-naïve idiopathic MCD patients and healthy controls. The CXCL9, CXCL11, CXCL1 concentrations and APRIL were higher in the patient group than in the healthy control group. A permutation test was used. An asterisk means that the P value is less than 0.05. MCD, multicentric Castleman disease; APRIL, proliferation-inducing ligand; NS, means no significant difference.
