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. 2022 May;14(5):1319–1331. doi: 10.21037/jtd-21-1713

Table 3. Clinical characteristics in patients admitted to ICU due to COVID-19 and with SARS-CoV-2 as a comorbidity.

Variables Patients admitted due to COVID-19 Patients with SARS-CoV-2 as comorbidity P value
N (%) 50 (82.0) 11 (18.0)
Age (years) 66.3±13.4 67.2±13.7 0.83
Sex, n (% women) 23 (46.0) 4 (36.4) 0.74
BMI (kg/m²) 31.4±7.4 30.1±7.7 0.61
Any comorbidity, n (%) 45 (90.0) 11 (100.0) 0.57
   Hypertension 29 (58.0) 5 (45.5) 0.51
   Diabetes 23 (46.0) 4 (36.4) 0.74
   ASCVD 17 (34.0) 9 (81.8) 0.006
   Chronic kidney disease 5 (10.0) 6 (54.5) 0.003
SOFA score on admission 5.6±2.7 5.5±3.7 0.92
SOFA score after 24 h 7.1±3.7 6.6±3.8 0.69
Charlson Comorbidity Index 3.7±2.2 5.2±2.6 0.051
pO2/FiO2 (mmHg)
   On admission 151±93 302±127 <0.0001
   After 24 h 137±72 253±118 0.009
   Lowest value 101±58 126±129 0.009
Any ARDS, n (%) 45 (90.0) 3 (27.3) <0.0001
   Mild 3 (6.0) 0 (0) 1.00
   Moderate 9 (18.0) 3 (27.3) 0.68
   Severe 33 (66.0) 0 (0) <0.0001
Any complication, n (%) 35 (70.0) 8 (72.7) 1.00
   CPR 12 (24.0) 2 (18.2) 1.00
   Encephalopathy/confusion 13 (26.0) 4 (36.4) 0.48
   Heart failure 10 (20.0) 4 (36.4) 0.26
   Acute renal failure 8 (16.0) 4 (36.4) 0.20
   Septic shock 6 (12.0) 4 (36.4) 0.07
Length of ICU stay, median (IQR) (days) 5.5 (2; 14) 7 (2; 19) 0.99
Intubation, n (%) 28 (56.0) 3 (27.3) 0.11
Mortality, n (%) 22 (44.0) 5 (45.5) 1.00

Data were presented as mean ± standard deviation if not otherwise specified. ICU, intensive care unit; COVID-19, coronavirus disease 2019; SARS-CoV-2, severe acute respiratory syndrome coronavirus type 2; BMI, body mass index; ASCVD, atherosclerotic cardiovascular disease; SOFA, sepsis organ failure assessment; pO2, partial pressure of oxygen; FiO2, inspiratory oxygen fraction; ARDS, acute respiratory distress syndrome; CPR, cardio-pulmonary resuscitation; IQR, interquartile range.