Table 3. Clinical characteristics in patients admitted to ICU due to COVID-19 and with SARS-CoV-2 as a comorbidity.
Variables | Patients admitted due to COVID-19 | Patients with SARS-CoV-2 as comorbidity | P value |
---|---|---|---|
N (%) | 50 (82.0) | 11 (18.0) | – |
Age (years) | 66.3±13.4 | 67.2±13.7 | 0.83 |
Sex, n (% women) | 23 (46.0) | 4 (36.4) | 0.74 |
BMI (kg/m²) | 31.4±7.4 | 30.1±7.7 | 0.61 |
Any comorbidity, n (%) | 45 (90.0) | 11 (100.0) | 0.57 |
Hypertension | 29 (58.0) | 5 (45.5) | 0.51 |
Diabetes | 23 (46.0) | 4 (36.4) | 0.74 |
ASCVD | 17 (34.0) | 9 (81.8) | 0.006 |
Chronic kidney disease | 5 (10.0) | 6 (54.5) | 0.003 |
SOFA score on admission | 5.6±2.7 | 5.5±3.7 | 0.92 |
SOFA score after 24 h | 7.1±3.7 | 6.6±3.8 | 0.69 |
Charlson Comorbidity Index | 3.7±2.2 | 5.2±2.6 | 0.051 |
pO2/FiO2 (mmHg) | |||
On admission | 151±93 | 302±127 | <0.0001 |
After 24 h | 137±72 | 253±118 | 0.009 |
Lowest value | 101±58 | 126±129 | 0.009 |
Any ARDS, n (%) | 45 (90.0) | 3 (27.3) | <0.0001 |
Mild | 3 (6.0) | 0 (0) | 1.00 |
Moderate | 9 (18.0) | 3 (27.3) | 0.68 |
Severe | 33 (66.0) | 0 (0) | <0.0001 |
Any complication, n (%) | 35 (70.0) | 8 (72.7) | 1.00 |
CPR | 12 (24.0) | 2 (18.2) | 1.00 |
Encephalopathy/confusion | 13 (26.0) | 4 (36.4) | 0.48 |
Heart failure | 10 (20.0) | 4 (36.4) | 0.26 |
Acute renal failure | 8 (16.0) | 4 (36.4) | 0.20 |
Septic shock | 6 (12.0) | 4 (36.4) | 0.07 |
Length of ICU stay, median (IQR) (days) | 5.5 (2; 14) | 7 (2; 19) | 0.99 |
Intubation, n (%) | 28 (56.0) | 3 (27.3) | 0.11 |
Mortality, n (%) | 22 (44.0) | 5 (45.5) | 1.00 |
Data were presented as mean ± standard deviation if not otherwise specified. ICU, intensive care unit; COVID-19, coronavirus disease 2019; SARS-CoV-2, severe acute respiratory syndrome coronavirus type 2; BMI, body mass index; ASCVD, atherosclerotic cardiovascular disease; SOFA, sepsis organ failure assessment; pO2, partial pressure of oxygen; FiO2, inspiratory oxygen fraction; ARDS, acute respiratory distress syndrome; CPR, cardio-pulmonary resuscitation; IQR, interquartile range.