Table 3. Correlation analysis between sST2 and clinical detection indexes.
Variables | HF group (n=186) | HF-AF group (n=120) | |||
---|---|---|---|---|---|
r value | P value | r value | P value | ||
Sex | 0.045 | 0.539 | –0.068 | 0.462 | |
Age | 0.169* | 0.021 | 0.287** | 0.001 | |
Systolic blood pressure | 0.041 | 0.578 | 0.008 | 0.932 | |
Diastolic blood pressure | 0.094 | 0.203 | 0.043 | 0.642 | |
Smoking | 0.204** | 0.005 | 0.077 | 0.406 | |
Drinking | 0.125 | 0.090 | 0.051 | 0.578 | |
Hypertension | –0.017 | 0.820 | 0.150 | 0.101 | |
Diabetes | –0.023 | 0.754 | –0.143 | 0.118 | |
Cardiomyopathy | –0.210** | 0.004 | 0.019 | 0.839 | |
Coronary heart disease | 0.158* | 0.031 | –0.026 | 0.777 | |
Valvular disease | –0.156* | 0.034 | –0.026 | 0.779 | |
NYHA | 0.147* | 0.045 | 0.470** | <0.0001 | |
LVEF | –0.345** | <0.0001 | –0.259** | 0.004 | |
LVD | 0.200** | 0.006 | 0.311** | 0.001 | |
LAD | 0.231** | 0.001 | 0.107 | 0.249 | |
ALT | 0.100 | 0.174 | –0.021 | 0.819 | |
WBC | 0.136 | 0.064 | 0.145 | 0.114 | |
RBC | –0.073 | 0.320 | –0.090 | 0.330 | |
Hemoglobin | –0.107 | 0.148 | –0.188* | 0.039 | |
Platelets | 0.145* | 0.049 | –0.037 | 0.688 | |
Serum creatinine | 0.195** | 0.008 | 0.320** | <0.0001 | |
NT-proBNP | 0.474** | <0.0001 | 0.540** | <0.0001 | |
D-dimer | 0.336** | <0.0001 | 0.322** | <0.0001 | |
Glomerular filtration rate | –0.213** | 0.003 | –0.283** | 0.002 | |
Body mass index | –0.093 | 0.209 | –0.065 | 0.484 |
*, P<0.05; **, P<0.01. sST2, soluble suppression of tumorigenicity 2; HF, heart failure; AF, atrial fibrillation; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; LVD, left ventricular end-diastolic diameter; LAD, left atrial diameter; ALT, alanine aminotransferase; WBC, white blood cell; RBC, red blood cell; NT-proBNP, NT-pro-brain natriuretic peptide.