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Residue–residue contact frequencies of α-synuclein monomer in (a) the absence and (b) in the presence of the SK9 segment. Data were averaged over the final 2.0 μs of each trajectory. The differences between the two frequencies are shown in (c) while we plot in (d) the corresponding difference in the average lifetime of contacts, i.e, how much longer on average a contact persists in presence of SK9 compared to its average lifetime in the control simulation.
