. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: Obesity (Silver Spring). 2021 Aug 4;29(9):1554–1564. doi: 10.1002/oby.23228

TABLE 3.

Ciude and adjusted OR and 95% CI for ASD or DD^a per prepregnancy maternal BMI categories

	ASD		ASD with ID		ASD without ID		DD
	Crude	Adjusted^b	Crude	Adjusted^b	Crude	Adjusted^b	Crude	Adjusted^b
Maternal exposure	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
	N° cases = 1,118		N° cases = 686		N° cases = 418		N° cases = 1,544
	N° controls = 1,592		N° controls = 1,592		N° controls = 1,592		N° controls = 1,592
Prepregnancy BMI
Underweight	1.09 (0.70–1.71)	0.99 (0.62–1.58)	1.03 (0.59–1.79)	0.89 (0.50–1.60)	1.04 (0.56–1.94)	1.04 (0.55–1.96)	0.98 (0.64–1.48)	0.89 (0.58–1.37)
Normal weight	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Overweight	1.28 (1.06–1.54)	1.12 (0.92–1.37)	1.43 (1.15–1.79)	1.17 (0.92–1.48)	1.03 (0.78–1.35)	1.03 (0.78–1.37)	1.26 (1.06–1.49)	1.09 (0.91–1.30)
Obesity Class 1	1.46 (1.13–1.89)	1.15 (0.88–1.52)	1.79 (1.34–2.39)	1.25 (0.92–1.72)	0.98 (0.66–1.45)	0.99 (0.66–1.49)	1.47 (1.16–1.86)	1.21 (0.95–1.55)
Obesity Class 2/3	2.54 (1.93–3.34)	1.87 (1.40–2.51)	2.69 (1.97–3.67)	1.71 (1.22–2.40)	2.34 (1.64–3.35)	2.30 (1.57–3.38)	2.07 (1.59–2.69)	1.61 (1.22–2.13)

Abbreviations: ASD, autism spectrum disorder; DD, developmental disorders; ID. intellectual disability (IQ ≤ 70); OR, odds ratio.

Compared with population-based control group (n = 1,633).

Adjusted for maternal age, education, race/ethnicity, parity, smoking, income, and site (categorized as in Table 1).