Lung fungal burdens of dogs vaccinated twice, once, or not at all with Δcps1. Differences between the 10 K PB, 50 K PB, and 100 K PB groups were not significant (P = 0.37), so they were combined for further comparison. Prime/boost significantly reduced total lung fungal burdens compared to prime only (100 K P) or no vaccination (Control) eight weeks after intratracheal inoculation of dogs with 1 × 104 Silveira arthroconidia. Lung fungal burdens were not significantly reduced by prime only vs. no vaccine (P = 0.3). Bar = median. (Statistical analysis - Kruskal-Wallis).