Table 3.

Toxicity profile of selected metabolites.

Sl. No	Metabolites	Toxicity predictors
		AMES toxicity	hERG I inhibitor	hERG II inhibitor	Oral Rat Acute Toxicity (LD50)	Oral Rat Chronic Toxicity (LOAEL)	Hepatotoxicity	Skin Sensitisation
	Unit	Categorical (Yes/No)	Categorical (Yes/No)	Categorical (Yes/No)	Numeric (mol/kg)	Numeric (log mg/kg)	Categorical (Yes/No)	Categorical (Yes/No)
1	Semicochliodinol A	NO	NO	YES	2.58	2.832	YES	NO
2	Semicochliodinol B	NO	NO	YES	2.644	2.74	YES	NO
3	SQ-02-S-L2	NO	NO	NO	2.38	2.238	YES	NO
4	Chromophilone I, iso	NO	NO	NO	2.197	0.711	NO	NO
5	L-696,474	NO	NO	NO	2.972	0.631	YES	NO
6	F13459	NO	NO	NO	2.436	3.145	NO	NO
7	SQ-02-S-V1	NO	NO	NO	2.945	2.447	YES	NO
8	Stachyflin	NO	NO	NO	2.219	0.063	YES	NO
9	L-696,475
10	L-697,318	NO	NO	NO	3.07	0.633	YES	NO
11	Stachyflin, acetyl	NO	NO	NO	2.129	1.782	NO	NO
12	A-108836	NO	NO	NO	2.323	2.532	NO	NO
13	Integracide A (A-108835)	NO	NO	NO	2.409	2.423	NO	NO
14	Fleephilone	YES	NO	NO	2.53	1.777	NO	NO
15	Trichothecin	NO	NO	NO	2.487	1.519	NO	NO
16	Phycomysterol A	NO	NO	YES	2.332	0.845	NO	NO
17	Flazin	NO	NO	NO	2.696	1.321	YES	NO
18	Terpestacin	NO	NO	NO	2.437	1.785	NO	NO