Table 2.
Multivariable Models of Lung Re-Expansion and Mortality after Palliative Radiotherapy for Pulmonary Obstruction
| Re-expansiona |
Overall mortalityb |
|||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% confidence interval | p | Hazard ratio | 95% confidence interval | p | |
| Age | 0.99 | 0.96–1.02 | 0.60 | 1.00 | 0.98–1.03 | 0.77 |
| Histology (vs. NSCLC) | ||||||
| SCLC | 0.83 | 0.21–3.23 | 0.78 | 1.06 | 0.50–2.25 | 0.88 |
| Metastasis | 0.89 | 0.31–2.57 | 0.84 | 0.34 | 0.14–0.82 | 0.02 |
| ECOG 3–4 (vs. 1–2) | 0.71 | 0.30–1.70 | 0.44 | 2.70 | 1.57–4.66 | <0.01 |
| Extent of obstruction (entire lung vs. lobar) | 1.76 | 0.50–6.12 | 0.38 | 0.89 | 0.43–1.84 | 0.75 |
| Tumor size <6 cm (vs. ≥6 cm) | 2.16 | 0.92–5.09 | 0.08 | 0.53 | 0.29–0.95 | 0.03 |
| Inpatient (vs. outpatient) | 0.44 | 0.17–1.12 | 0.08 | 1.74 | 0.94–3.20 | 0.08 |
| Obstruction 30+ days (vs. <30 days) | 0.58 | 0.24–1.41 | 0.23 | 0.51 | 0.29–0.93 | 0.03 |
| No. of fractions (vs. 1) | ||||||
| 2–5 | 2.31 | 0.54–9.96 | 0.26 | 0.34 | 0.15–0.77 | 0.01 |
| 10 | 2.41 | 0.69–8.36 | 0.17 | 0.24 | 0.11–0.50 | <0.01 |
| Re-expansion | — | — | — | 0.28 | 0.15–0.52 | <0.01 |
Competing risk regression.
Cox proportional hazards.