Table 1.
Phase Ib | Phase II | ||
---|---|---|---|
RO4929097 plus vismodegib | RO4929097 | RO4929097 plus vismodegib | |
Total n | 9 | 34 | 33 |
Age (median) | 60 | 56 | 46 |
Male sex, n (%) | 5 (55.6%) | 20 (58.8%) | 18 (54.5%) |
Histology, n (%) | |||
Other* | 8 (66.7%) | 25 (73.5%) | 23 (69.7%) |
ECOG performance status, n (%) | |||
2 | 0 (0) | 0 (0) | 1 (3.0) |
Number of prior therapies (median) | 4 | 2 | 3 |