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. Author manuscript; available in PMC: 2022 Jun 10.
Published in final edited form as: Clin Cancer Res. 2022 Apr 14;28(8):1586–1594. doi: 10.1158/1078-0432.CCR-21-3874

Table 1.

Patient demographics and tumor characteristics.

Phase Ib Phase II
RO4929097 plus vismodegib RO4929097 RO4929097 plus vismodegib
Total n 9 34 33
Age (median) 60 56 46
Male sex, n (%) 5 (55.6%) 20 (58.8%) 18 (54.5%)
Histology, n (%)
 Liposarcoma 3 (33.3%) 9 (26.5%) 10 (30.3%)
 Other* 8 (66.7%) 25 (73.5%) 23 (69.7%)
ECOG performance status, n (%)
 0–1 9 (100%) 34 (100%) 32 (97%)
 2 0 (0) 0 (0) 1 (3.0)
Number of prior therapies (median) 4 2 3