Fig 1. Pipeline for selection of X chromosome biallelic SNPs with global MAF ≥5%, presumed to be of high quality, from the 1000 Genomes Project phase 3 data on GRCh37.

Variants were placed into the NPR, PAR1, PAR2, and PAR3 regions based on positions available from The Genome Reference Consortium and [19]. For detailed counts of variant types and global MAF by regions, see S1 Table.