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. 2022 May 31;18(5):e1010231. doi: 10.1371/journal.pgen.1010231

Fig 2. Manhattan plot for testing for sex difference in MAF across the X chromosome from the 1000 Genomes Project phase 3 data on GRCh37.

Fig 2

A: sdMAF p-values for bi-allelic SNPs with global MAF ≥5% presumed to be of high quality. SNPs in the PAR1, PAR2 and PAR3 regions are plotted in grey, with PAR3 located around 90 Mb. Y-axis is −log10(sdMAF p-values) and p-values >0.1 are plotted as 0.1 (1 on −log10 scale) for better visualization. The dashed red line represents 5e-8 (7.3 on the −log10 scale). B: Female—Male sdMAF for the same SNPs in part A. For Zoomed-in plots for the PAR1, PAR2 and PAR3 regions see Figs 4, 5 and 6, respectively.