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. Author manuscript; available in PMC: 2023 Apr 5.
Published in final edited form as: J Am Coll Cardiol. 2022 Apr 5;79(13):1254–1265. doi: 10.1016/j.jacc.2022.01.038

Central illustration. Effects of experimental sleep restriction on obesity risk.

Central illustration.

Twelve healthy individuals completed a randomized, controlled, crossover, 21-day inpatient study of sleep restriction (4-hour sleep opportunity) vs control sleep (9-hour sleep opportunity). During sleep restriction participants increased their daily energy intake by 308 Kcal compared to control sleep. Body weight increased in response to sleep restriction vs control sleep, with significant accumulation of abdominal visceral fat (~11%).