Table 1. Summary of datasets.

Summary of datasets analyzed in this study including the number of mice n (see also Fig. 1). For information on the size of the images and extracted networks, see table S1.

Dataset	Type	Model	Experimental conditions
Multiphoton intravital 3D microscopy	Dynamic (over multiple days)	Mouse colorectal cancer in mice	1. Control (n = 7)
			2. DC101 (decreases sprouting, n = 5)
			3. Anti-Dll4 (increases sprouting, n = 3)
			4. Irradiated (single-dose 15 Gy, n = 5)
			5. Irradiated (fractionated-dose 5 × 3 Gy, n = 4)
Multispectral fluorescence ultramicroscopy	Static	Human breast cancer in mice	1. Control (n = 18)
			2. Bevacizumab (n = 13)