Table 4.

Performance of Microbial Cell-Free DNA Test Versus Index Blood Culture by Pathogen Type

	Any mcfDNA Versus Index Blood Culture, N = 140			Index mcfDNA Versus Index Blood Culture, N = 137
Study Group	mcfDNA Positive	mcfDNA Negative	Agreement, %	mcfDNA Positive	mcfDNA Negative	Agreement, %
Gram-negative bacteremia	68	6	91.9	66	7	90.4
Staphylococcus aureus bacteremia	57	9	86.4	50	14	78.1
Methicillin-resistant S. aureus	29	2	93.5	28	4	87.5
Methicillin-susceptible S. aureus	28	7	80	22	10	68.8
Cumulative	125	15	89.3	116	21	84.7
Controla	n/a	n/a	n/a	9	26	n/a

Percent agreement of any of the mcfDNA tests (n = 140) and index mcfDNA (n = 137) obtained for each case vs the index blood culture for all patients with positive blood cultures, listed by type of bacteremia.

Abbreviations: mcfDNA, microbial cell-free DNA; n/a, not applicable.

^a The control group consisted of patients who did not have a suspicion for infection during their admission and did not have blood cultures performed; thus, no agreement could be calculated.