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. 2021 Sep 1;74(11):2001–2009. doi: 10.1093/cid/ciab744

Table 5.

Human Immunodeficiency Virus (HIV) Drug Resistance in Infants at Time of Diagnosis by Antiretroviral Class and Timing of Vertical Transmission

In utero or Peripartum Vertical Transmission Breastfeeding Vertical Transmission
Number and Antiretroviral Drug Class With Resistance Mutations Detected n = 41 (53.3%) n = 36 (46.7%)
NRTI
 Single 3 (8.3%)
 Multiple
NNRTI
 Single 5 (12.2%) 8 (22.2%)
 Multiple 7 (19.4%)
NRTI and NNRTI 1 (2.8%)
Total number (%; 95% CI) 5 (12.5%; 4.1%, 26.2%) 19 (52.8%; 35.5%, 69.6%)

Abbreviations: CI, confidence interval; NRTI, nucleoside reverse transcriptase inhibitors; NNRTI, non-nucleoside reverse transcriptase inhibitors.