Table 2. Clinical and immunohistological characteristics of patients with gastrointestinal schwannomas.
Schwannoma location | Esophagus | 6 | 13.6 |
Stomach | 17 | 38.6 | |
Pancreas | 1 | 2.3 | |
Small bowel | 6 | 13.6 | |
Colorectal | 14 | 31.8 | |
Symptoms | Abdominal pain | 7 | 15.9 |
Bleeding | 4 | 9.1 | |
Dyspepsia | 6 | 13.7 | |
Dysphagia | 3 | 6.8 | |
Initial identification | CT | 14 | 31.8 |
Colonoscopy | 11 | 25 | |
EUS | 8 | 18.2 | |
EGD | 4 | 9.1 | |
MRI | 4 | 9.09 | |
No imaging or endoscopy | 3 | 6.8 | |
Biopsy sample | Surgical Specimen | 23 | 52.3 |
EUS | 10 | 22.7 | |
EGD | 7 | 15.9 | |
Colonoscopy | 4 | 9.1 | |
Labs at diagnosis | Lab | Mean (SD) | Median |
Hgb | 12.8 (1.9) | 13.0 | |
HCT | 38.8 (5.1) | 39.4 | |
Platelet | 251 (81) | 254 | |
BUN | 15.7 (8.5) | 14.0 | |
Creatinine | 0.88 (0.40) | 0.80 | |
Albumin | 4.09 (0.60) | 4.3 | |
Pathology | |||
Size (mm) | Esophagus | 22.8 (18.3) | 20.0 |
Stomach | 37.7 (23.6) | 33.5 | |
Pancreas | 4 (NA) | 4 | |
Small Bowel | 21 (17.9) | 15.5 | |
Colorectal | 24.1 (18.7) | 17 | |
Histology | N (44) | % | |
Cystic | 0 | 0 | |
Solid | 29 | 82.9 | |
Mixed | 5 | 14.3 | |
Necrosis | 1 | 2.8 | |
Immunological markers | N (44) | Percentage | |
S100 | 28 | 63.6 | |
S100 + Ki-67 | 12 | 27.2 | |
S100 + GFAP | 1 | 2.3 | |
S100 + SMA | 1 | 2.3 | |
S100 + CD34 | 1 | 2.3 | |
Not available | 1 | 2.3 |
CT, computed tomography; EUS, endoscopic ultrasound; EGD, esophagogastroduodenoscopy; MRI, magnetic resonance imaging; SD, standard deviation; HgB, hemoglobin; HCT, hematocrit; BUN, blood urea nitrogen.