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. 2022 May 11;32(2):587–592. doi: 10.1007/s00062-022-01175-w

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Five mitotic features were observed in 10 high-power fields (a, arrow). The scale bar represents 50 µm. Mitotic features are also visualized in the immunohistochemical reaction for phospho-HH3 (brown, b) as indicated by asterisks. Around 10% of the tumor cells were labelled in the immunohistochemical reaction for proliferation marker MIB-1 (c). Hematoxylin (blue) was used as counterstaining (b, c). Scale bar (b, c): 100 µm