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. 2022 May 2;45(3):415–428. doi: 10.1007/s13402-022-00674-9

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Fig. 1 — Melatonin causes decreases in cellular calcium levels and intracellular oxidants. Melatonin treatment induces a decrease in (a) cytosolic calcium, (b) mitochondrial calcium and (c) intracellular peroxide levels in both cancer cell lines tested. Dashed line indicates control group levels. * p ≤ 0.05 vs control group (vehicle-treated cells)