Table 1.
Demographics of Study Population | |||||
---|---|---|---|---|---|
Controls | PWS | ||||
(n = 14) | Total (n = 31) | Psychosis (n = 7) | No Psychosis (n = 25) | ||
Age (mean [SD], years) | 31.21 [8.65] | 27.23 [11.63] | 30.57 [14.85] | 26.25 [10.70] | |
Sex | m | 9 (64.3%) | 19 (61.3%) | 6 (85.7%) | 13 (54.2%) |
f | 5 (35.7%) | 12 (38.7%) | 1 (14.3%) | 11 (45.8%) | |
BMI (mean [SD], kg/m²) | 26.62 [5.46] | 27.98 [7.38] | 31,28 [12.16] | 27.02 [5.31] | |
Subtype | Del | / | 14 (4 Del I, 9 Del II, 1 ns) | / | 14 (4 Del I, 9 Del II, 1 ns) |
mUPD/IC | / | 17 (9 mUPD, 4 IC, 4 ns) | 7 (2 mUPD, 2 IC, 3 ns) | 10 (7 mUPD, 2 IC, 1 ns) |
Study population is grouped by controls and PWS. PWS individuals are then further grouped by history of psychosis vs no history of psychosis. Abbreviations: Del deletion, Del I deletion type I, Del II deletion tye II, mUPD maternal uniparental disomy, IC imprinting defect, ns, not specified because no differentiation of specific subtype could be obtained (Del I vs Del II or UPD vs IC) due to different reasons (e.g. no blood from the parents could be obtained).