Table 2.
Changes in pH and iron content at baseline t0, as well as t1 (one week) and t2 (four weeks) of SFOH administration.
| P | S | Saliva | Feces | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Native | Stimulated | Supernatant | Sediment | |||||||
| pH | pH | Total Fe(µg/ml) | Fe(2+) (µg/ml) | pH | Total Fe(µg/ml) | Fe(2+) (µg/ml) | Total Fe(µg/ml) | Fe(2+) (µg/ml) |
||
| A01 | V0 | 7.5 | 8.5 | 0 | 0 | 8 | 0 | 0 | 0 | 0 |
| A01 | V1 | 7 | 8.5 | 0.016 | 0 | 7.8 | 750 | 15 | 750 | 50 |
| A01 | V2 | 8 | 8.5 | 0 | 0 | 6.8 | 20 | 3 | 30 | 10 |
| A02 | V0 | 7 | 8.3 | 0 | 0 | 7.2 | 0 | 0 | 0 | 0 |
| A02 | V1 | 6 | 8.3 | n.m | 2 | 5.5 | 250 | 20 | 500 | 50 |
| A02 | V2 | 7 | 8 | n.m | 2 | 7 | 20 | 10 | 60 | 40 |
| A05 | V0 | 5.5 | 8 | 0 | 0 | 7.5 | 0 | 0 | 0 | 0 |
| A05 | V1 | 5.5 | 8 | 0.004 | 0 | 7.5 | 20 | 10 | 750 | 500 |
| A05 | V2 | 7 | 7 | 0 | 0 | 7.5 | 15 | 10 | 750 | 150 |
| A08 | V0 | 7.5 | 8 | 0 | 0 | 8 | 0 | 0 | 0 | 0 |
| A08 | V1 | 7.5 | 8 | 0 | 0 | 8 | 25 | 25 | 250 | 250 |
| A08 | V2 | 7.5 | 8.5 | 0 | 0 | 7.5 | 3 | 3 | 50 | 50 |
| A09 | V0 | 8.5 | 9 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A09 | V1 | 8.5 | 7 | 0 | 0 | 7 | 3 | 3 | 50 | 10 |
| A09 | V2 | 6.5 | 8.5 | 0 | 0 | 7 | 10 | 3 | 50 | 25 |
| A12 | V0 | 7 | 7.5 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A12 | V1 | 7 | 8 | n.m | 3 | 7.5 | 25 | 10 | 250 | 250 |
| A12 | V2 | 8 | 8.5 | 0.16 | 0 | 8 | 3 | 3 | 100 | 100 |
| A13 | V0 | 7 | 8.5 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A13 | V1 | 8 | 8 | n.m | 1 | 6.5 | 10 | 3 | 250 | 50 |
| A13 | V2 | 7 | 8.5 | 0.008 | 0 | 7.5 | 10 | 3 | 500 | 25 |
| A15 | V0 | 6.5 | 8 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A15 | V1 | 6.5 | 8.5 | 0 | 0 | 8 | 3 | 0 | 500 | 50 |
| A15 | V2 | 6.5 | 8.5 | 0 | 0 | 7 | 3 | 3 | 50 | 25 |
| A16 | V0 | 8 | 8.5 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A16 | V1 | 8 | 8 | 0 | 0 | 8 | 10 | 10 | 50 | 25 |
| A16 | V2 | Drop out | ||||||||
| A17 | V0 | 7 | 8 | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A17 | V1 | 5.5 | 8 | 0 | 0 | 5.5 | 10 | 3 | 250 | 50 |
| A17 | V2 | Drop out | ||||||||
| A19 | V0 | 7 | n.d | 0 | 0 | 7 | 0 | 0 | 0 | 0 |
| A19 | V1 | 5.5 | 7.5 | n.m | 3 | 6.5 | 0 | 0 | 3 | 0 |
| A19 | V2 | Drop out | ||||||||
P: patient number, S: time-point (t0, t1, t2) related sample number (V0, V1, V2), n.d. not determined, at V0, the patient did not produce any additional saliva after stimulation. n.m. not measurable: at low concentrations, Fe test kits showed diffuse colors or discrepancies and these cases were excluded as not reliable.