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. 2022 Jun 10;12:9654. doi: 10.1038/s41598-022-13572-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Characterization of PVA-MNP hydrogels. (A) FTIR spectra of all samples. (B) DLS data for pure MNPs, MNP-CA and MNP-CA-Ac samples indicating differences in particles sizes. (C) Zeta potential data for pure MNPs, MNP-CA and MNP-CA-Ac samples indicating differences in surface charges. (D) TGA data for commercial citric and acetaminophen. (E) TGA data for MNP-CA and MNP-CA-Ac samples. (F, G) SEM images of freeze-dried drug coated PVA-MNP hydrogels. (H) EDX data for SEM image G, where drug coated MNP distribution is depicted in red, indicating a homogeneous distribution of the MNP-CA-Ac system within the hydrogel.