Table 2.
Characteristic of critically ill patients, overall and depending on their response to corporeal rehabilitation care
| Parameter | N | All patients (n = 287) | Non-responders (n = 99) | Responders (n = 188) | p value |
|---|---|---|---|---|---|
| Patients’ characteristics | |||||
| Female gender | 287 | 164 (57%) | 44 (44%) | 120 (64%) | 0.002 |
| Age (years) | 287 | 59 [37–70] | 63 [48–72] | 55 [36–70] | 0.047 |
| Body mass index (kg/m2) | 257 | 25 [21–29] | 24 [21–28] | 24 [21–29] | 0.904 |
| Past medical history | |||||
| Respiratory disease | 287 | 101 (35%) | 34 (34%) | 67 (36%) | 0.827 |
| Cardiac disease | 287 | 135 (47%) | 55 (56%) | 80 (43%) | 0.036 |
| Neurological disease | 287 | 35 (12%) | 10 (10%) | 25 (13%) | 0.431 |
| Cirrhosis | 287 | 7 (2%) | 3 (3%) | 4 (2%) | 0.696 |
| Cancer | 287 | 44 (15%) | 19 (19%) | 25 (13%) | 0.188 |
| Blood cancers | 287 | 26 (9%) | 14 (14%) | 12 (6%) | 0.030 |
| Sickle cell disease | 287 | 65 (23%) | 16 (16%) | 49 (26%) | 0.057 |
| Chronic kidney failure | 287 | 12 (4%) | 4 (4%) | 8 (4%) | > 0.99 |
| Psychiatric disease | 287 | 30 (11%) | 12 (12%) | 18 (10%) | 0.503 |
| Alcohol consumption | 287 | 26 (9%) | 8 (8%) | 18 (10%) | 0.675 |
| Drug addiction | 287 | 8 (3%) | 1 (1%) | 7 (4%) | 0.270 |
| Long term treatments | |||||
| Benzodiazepine | 287 | 27 (9%) | 12 (12%) | 15 (8%) | 0.253 |
| Antidepressive drug | 287 | 32 (11%) | 11 (11%) | 21 (11%) | 0.988 |
| Neuroleptic | 287 | 18 (6%) | 8 (8%) | 10 (5%) | 0.359 |
| Between ICU admission and inclusion | |||||
| SAPS 2 score | 281 | 32 [18–47] | 36 [22–48] | 32 [15–47] | 0.125 |
| Medical admission | 287 | 262 (91%) | 87 (88%) | 175 (93%) | 0.137 |
| Infection | 287 | 174 (61%) | 67 (68%) | 107 (57%) | 0.076 |
| Septic shock | 287 | 62 (22%) | 24 (24%) | 38 (20%) | 0.430 |
| Orotracheal intubation | 287 | 73 (25%) | 23 (23%) | 50 (27%) | 0.534 |
| Tracheostomy | 287 | 11 (4%) | 4 (4%) | 7 (4%) | > 0.99 |
| ARDS | 287 | 29 (10%) | 13 (13%) | 16 (9%) | 0.217 |
| 24 h preceding inclusion | |||||
| Maximal SAP (mmHg) | 287 | 143 [129–157] | 140 [130–156] | 145 [129–158] | 0.283 |
| Minimal SAP (mmHg) | 287 | 81 [72–90] | 80 [73–89] | 81 [72–90] | 0.810 |
| Maximal RASS score | 287 | 0 [0–0] | 0 [0–0] | 0 [0–0] | 0.980 |
| Minimal RASS score | 287 | 0 [0–0] | 0 [0–0] | 0 [0–0] | 0.426 |
| Maximal temperature (°C) | 287 | 37 [37–38] | 37 [37–38] | 37 [37–38] | 0.999 |
| Maximal heart rate (bpm) | 287 | 99 [88–114] | 99 [84–109] | 99 [89–116] | 0.202 |
| Minimal heart rate (bpm) | 287 | 80 [69–91] | 75 [64–87] | 82 [71–93] | 0.004 |
| Shock | 287 | 16 (6%) | 7 (7%) | 9 (5%) | 0.423 |
| Noradrenaline infusiona | 287 | 12 (4%) | 4 (4%) | 8 (4%) | > 0.99 |
| Dobutaminea | 287 | 5 (2%) | 4 (4%) | 1 (1%) | 0.050 |
| Antihypertensive drug | 287 | 37 (13%) | 11 (11%) | 26 (14%) | 0.514 |
| Continuous sedation or analgesia | 287 | 16 (6%) | 2 (2%) | 14 (7%) | 0.057 |
| Propofol | 287 | 5 (2%) | 0 (0%) | 5 (3%) | 0.168 |
| Fentanyl | 287 | 2 (1%) | 0 (0%) | 2 (1%) | 0.547 |
| Sufentanyl | 287 | 12 (4%) | 2 (2%) | 10 (5%) | 0.229 |
| Morphine | 287 | 73 (25%) | 22 (22%) | 51 (27%) | 0.364 |
| Morphine cumulative dose (mg) | 33 | 57 [6–221] | 35 [5–113] | 120 [6–324] | 0.240 |
| Neuroleptic | 287 | 2 (1%) | 0 (0%) | 2 (1%) | 0.547 |
CRC corporeal rehabilitation care, ICU intensive care unit, SAPS Simplified Acute Physiologic Score, ARDS Acute Respiratory Distress Syndrome, SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, RASS Richmond Agitation-Sedation Scale
aDose did not change during CRC