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Case 2 showing a 1.4 cm lip white plaque (a); biopsy showing ulcerated squamous mucosa with adjacent pseudoepitheliomatous hyperplasia and a rich acute inflammatory infiltrate (b and c, H&E stain); and immunostain of T. Pallidum showing numerous T. Pallidum spirochetes (d and inset) (b, 100x; c and d, 400x)
