Table 1.
Demographic characteristics and comorbidities of patients newly diagnosed with chronic fatigue syndrome in Taiwan between 2000 and 2012 and of those in the control group
| Variable | CFS cohort | Non-CFS cohort | P-value |
|---|---|---|---|
| (n = 6306) | (n = 6306) | ||
| Gender | > 0.99 | ||
| Female | 3339 (52.9) | 3339 (52.9) | |
| Male | 2967 (47.1) | 2967 (47.1) | |
| Age at diagnosis of CFS | > 0.99 | ||
| ≤ 34 | 1350 (21.4) | 1350 (21.4) | |
| 35–64 | 3485 (55.3) | 3485 (55.3) | |
| ≥ 65 | 1471 (23.3) | 1471 (23.3) | |
| Age at diagnosis of CFS(mean, SD)† | 50.6 (17.9) | 50.6 (18.0) | 0.80 |
| Comorbidity | |||
| Depression | 807 (12.8) | 407 (6.45) | < 0.0001 |
| Anxiety disorder | 2038 (32.3) | 1033 (16.4) | < 0.0001 |
| Insomnia | 2303 (36.5) | 1106 (17.5) | < 0.0001 |
| Suicide | 19 (0.30) | 12 (0.19) | 0.20 |
| Crohn's disease | 255 (4.04) | 121 (1.92) | < 0.0001 |
| Ulcerative colitis | 279 (4.42) | 138 (2.19) | < 0.0001 |
| Renal disease | 585 (9.28) | 427 (6.77) | < 0.0001 |
| T1DM | 78 (1.24) | 68 (1.08) | 0.40 |
| T2DM | 1473 (23.3) | 1068 (16.9) | < 0.0001 |
| Obesity | 93 (1.47) | 64 (1.01) | 0.01 |
| Gout | 1196 (18.9) | 702 (11.1) | < 0.0001 |
| Dyslipidemia | 2252 (35.7) | 1356 (21.5) | < 0.0001 |
| Malignancy | 407 (6.45) | 487 (7.72) | 0.01 |
| HIV | 3 (0.05) | 3 (0.05) | > 0.99 |
| Rheumatoid arthritis | 254 (4.03) | 155 (2.46) | < 0.0001 |
| Psoriasis | 94 (1.49) | 83 (1.32) | 0.40 |
| Ankylosing spondylitis | 53 (0.84) | 39 (0.62) | 0.14 |
| Lymphadenopathy | 132 (2.09) | 104 (1.65) | 0.06 |
| Hashimoto's thyroiditis | 13 (0.21) | 10 (0.16) | 0.53 |
| Sjogren's syndrome | 110 (1.74) | 71 (1.13) | 0.003 |
| Irritable bowel syndrome | 886 (14.1) | 423 (6.71) | < 0.0001 |
| Fibromyalgia | 4905 (77.8) | 4914 (77.9) | 0.85 |
| SLE | 4 (0.06) | 9 (0.14) | 0.16 |
| Herpes zoster | 341 (5.41) | 234 (3.71) | < 0.0001 |