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. 2022 Jun 11;20:266. doi: 10.1186/s12967-022-03470-z

Table 2.

Association of baseline conventional and unconventional lipid parameters and future diabetes

HR (95% CI)
Model 1 Model 2 Model 3 Model 4
HDL-C 0.32 (0.22, 0.47) 0.49 (0.33, 0.73) 0.55 (0.38, 0.81) 0.53 (0.36, 0.78)
TC 1.18 (1.05, 1.33) 1.13 (1.00, 1.28) 0.94 (0.83, 1.06) 0.92 (0.81, 1.04)
TG 1.48 (1.34, 1.63) 1.34 (1.20, 1.50) 1.21 (1.07, 1.36) 1.20 (1.06, 1.35)
LDL-C 1.27 (1.10, 1.46) 1.17 (1.01, 1.35) 0.94 (0.81, 1.09) 0.93 (0.80, 1.08)
Non-HDL-C 1.33 (1.19, 1.50) 1.21 (1.07, 1.37) 1.00 (0.88, 1.13) 0.99 (0.87, 1.12)
RC 4.55 (3.16, 6.55) 3.06 (2.03, 4.60) 1.72 (1.11, 2.67) 1.66 (1.07, 2.58)
TC/HDL-C ratio 1.34 (1.24, 1.44) 1.21 (1.12, 1.32) 1.11 (1.02, 1.21) 1.11 (1.02, 1.21)
TG/HDL-C ratio 1.34 (1.25, 1.42) 1.26 (1.16, 1.36) 1.19 (1.09, 1.30) 1.18 (1.08, 1.29)
Non-HDL/HDL-C ratio 1.34 (1.24, 1.44) 1.21 (1.12, 1.32) 1.11 (1.02, 1.21) 1.11 (1.02, 1.21)
LDL/HDL-C ratio 1.39 (1.26, 1.52) 1.24 (1.11, 1.37) 1.11 (1.00, 1.24) 1.12 (1.00, 1.24)
RC/HDL-C ratio 25.49 (9.69, 67.06) 8.13 (2.84, 23.24) 6.08 (2.17, 17.08) 6.75 (2.40, 18.98)

Model 1 adjusted for sex, age and BMI

Model 2 adjusted for sex, age, BMI, exercise habits, fatty liver, drinking status and smoking status

Model 3 adjusted for sex, age, BMI, exercise habits, fatty liver, drinking status, smoking status, SBP, FPG and HbA1c

Model 4 adjusted for sex, age, BMI, exercise habits, fatty liver, drinking status, smoking status, SBP, FPG, HbA1c, height, ALT, AST and GGT

HR hazard ratios; CI confidence interval; other abbreviations as in Table 1