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. 2022 Jun 10;22:261. doi: 10.1186/s12872-022-02693-8

Table 2.

Multiple centrality measures in the drug-target-disease network (top 21)

Nodes Subgragh Degree Eigenvector Information Closeness Betweenness
HFpEF 4.02E + 16 1505 0.703902 2.108198 0.855509 2,654,751
Dapagliflozin 1.53E + 14 145 0.043505 2.081154 0.354436 142,937.1
Canagliflozin 8.19E + 13 116 0.031785 2.073808 0.350064 106,420.2
Empagliflozin 6.63E + 13 111 0.028588 2.072172 0.349321 115,219.2
Ertugliflozin 6.50E + 13 107 0.028322 2.070733 0.348729 85,940.67
SLC5A2 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
SLC5A1 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
ADK 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
PDGFRB 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
ADORA2A 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
GBA 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
PDE5A 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
F3 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
CTSL 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
EGFR 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
GAPDH 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
MMP3 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
MMP1 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
P2RY12 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
JAK2 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
MME 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
MAPK1 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
ECE1 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
CDK2 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
MGAM 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079
SI 3.71E + 13 5 0.021382 1.562157 0.500761 7363.079