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. 2022 Jun 10;22:261. doi: 10.1186/s12872-022-02693-8

Table 4.

KEGG clusters with their representative enriched terms (top 20)

GO Category Description Count % Log10(P) Log10(Q)
hsa05200 KEGG Pathway Pathways in cancer 150 9.48 −83.58 −80.68
ko05206 KEGG Pathway MicroRNAs in cancer 109 6.89 −58.39 −56.10
ko04933 KEGG Pathway AGE-RAGE signaling pathway in diabetic complications 65 4.11 −56.03 −53.91
hsa05161 KEGG Pathway Hepatitis B 78 4.93 −49.13 −47.31
hsa05410 KEGG Pathway Hypertrophic cardiomyopathy (HCM) 54 3.72 −48.32 −46.54
hsa04024 KEGG Pathway cAMP signaling pathway 84 5.31 −45.78 −44.09
hsa05166 KEGG Pathway HTLV-I infection 85 5.37 −41.85 −40.27
hsa05145 KEGG Pathway Toxoplasmosis 58 3.66 −40.54 −39.00
hsa04060 KEGG Pathway Cytokine-cytokine receptor interaction 81 5.59 −39.00 −37.38
hsa04210 KEGG Pathway Apoptosis 60 3.79 −37.47 −36.10
hsa04010 KEGG Pathway MAPK signaling pathway 79 4.99 −36.46 −35.15
hsa05222 KEGG Pathway Small cell lung cancer 44 2.78 −32.03 −30.82
ko04932 KEGG Pathway Non-alcoholic fatty liver disease (NAFLD) 57 3.60 −31.99 −30.79
ko05323 KEGG Pathway Rheumatoid arthritis 44 3.03 −31.95 −30.61
hsa04066 KEGG Pathway HIF-1 signaling pathway 51 3.22 −31.56 −30.40
ko05144 KEGG Pathway Malaria 33 2.28 −30.49 −29.27
ko05146 KEGG Pathway Amoebiasis 44 3.03 −30.42 −29.21
hsa04640 KEGG Pathway Hematopoietic cell lineage 44 3.03 −30.18 −28.99
hsa04020 KEGG Pathway Calcium signaling pathway 60 3.79 −29.48 −28.38
ko04064 KEGG Pathway NF-kappa B signaling pathway 43 2.72 −27.91 −26.90

"Count" is the number of genes in the gene list with membership in the given ontology term. "%" is the percentage of all of the genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). "Log10(P)" is the P-value in log base 10. "Log10(Q)" is the multi-test adjusted P-value in log base 10