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. 2022 Jun 11;21:185. doi: 10.1186/s12936-022-04160-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Global probabilistic sensitivity analysis results showing incremental cost-effectiveness ratio estimates for varied levels of incidence. Black points represent individual simulation results. Horizontal lines represent alternative cost-effectiveness thresholds: green solid line = 0.5 * per capita gross domestic product (PCGDP); dotted and dashed blue line represents 1 * PCGDP, and red dotted line represents 3 * PCGDP. The grey curve represents median ICER estimates at varied baseline incidence using the base case assumption of case fatality rate and red line represents median ICER estimates assuming a case fatality rate 50% lower than base case scenarios. DALY, disability-adjusted life year; ICER, incremental cost-effectiveness ratio; PCGDP, per capita gross domestic product