Fig. 7.

Lysosome proteins in young and age, male and female mice. A Representative western blots for Lamp1, vATPase, mature Cathepsin B, and mature Cathepsin D. B Quantification of Lamp1 protein in combined and sex-separated groups. C Quantification of vATPase protein in combined and sex-separated groups. D Quantification of mature Cathepsin B protein in combined and sex-separated groups. E Quantification of mature Cathepsin D protein in combined and sex-separated groups. All values were corrected to GAPDH and are reported as means ± SEM, in A.U. The main effects of 2-way ANOVA are represented on a graph at p < 0.05. δ p < 0.05, post hoc significance. *p < 0.05, t-test between indicated groups. N = 10/male group, 8/female group