Table 1.

Animal body weight and muscle characteristics

	Combined		Male		Female		Statistics
	Young	Aged	Young	Aged	Young	Aged
Body mass (g)	30.73 ± 1.27	41.35 ± 1.91ϕ	34.65 ± 1.01	45.72 ± 2.45*,A	25.83 ± 0.976C	35.89 ± 1.62*,B,D	# †
Muscle mass (mg)
TA	51.41 ± 1.41	53.49 ± 3.95	54.61 ± 1.34	58.70 ± 3.95	47.43 ± 1.97δ	46.98 ± 5.58	†
Sol	10.32 ± 0.49	9.60 ± 0.76	10.01 ± 0.42	9.95 ± 0.926	10.51 ± 1.00	9.15 ± 1.32
Muscle mass (mg/g body weight)
TA	1.70 ± 0.06	1.31 ± 0.10ϕ	1.59 ± 0.05	1.30 ± 0.12*	1.85 ± 0.08	1.34 ± 0.17*,B	#
Sol	0.34 ± 0.03	0.24 ± 0.02ϕ	0.29 ± 0.02	0.22 ± 0.02*	0.41 ± 0.04C	0.26 ± 0.04*,B	# †

Body mass (g), muscle mass (mg), and muscle mass corrected for body weight (mg/g) in combined and sex-separated young and aged muscle. Values are means ± SEM. ϕ, p < 0.05, t-test between young and old in the combined analysis. In the sex-separated analysis, a two-way ANOVA was performed. #, p < 0.05 main effect of age; †, p < 0.05 main effect of sex; ⁋, p < 0.05 interaction of age and sex. “A” represents post hoc significance between young and aged within the male cohort, “B” represents post hoc significance between young and aged within the female cohort, “C” represents post hoc significance between young males and females, and “D” represents post hoc significance between aged males and females. Additionally, independent t-tests were run to compare young vs old within the same sex, *p < 0.05, and between male and females within the same age group, δ, p < 0.05. N = 10/male group, N = 8/female group