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. 2022 Jun 10;21:105. doi: 10.1186/s12933-022-01541-5

Table 3.

Absolute risk difference (per 1000 population over 10 years) of cardiovascular disease by the baseline, mean, and variability of TyG index

Predicted incidence per 1000 population over 10 yearsa Absolute risk difference per 1000 population over 10 yearsb
Baseline TyG index
 Tertile 1 51.2 (47.0 to 55.8) Reference
 Tertile 2 62.0 (57.9 to 66.3) 10.7 (4.8 to 16.7)
 Tertile 3 76.6 (67.3 to 87.1) 25.3 (12.0 to 38.6)
Mean TyG index
 Tertile 1 48.5 (44.4 to 53.0) Reference
 Tertile 2 60.5 (56.5 to 64.9) 12.0 (6.2 to 17.8)
 Tertile 3 82.8 (72.8 to 94.3) 34.3 (20.2 to 48.3)
TyG index variability
 Tertile 1 56.6 (52.8 to 60.8) Reference
 Tertile 2 58.7 (54.7 to 62.9) 2.1 (− 3.6 to 7.7)
 Tertile 3 63.0 (68.9 to 67.3) 6.3 (0.6 to 12.1)

TyG: triglyceride-glucose

aCalculated as CIFt=10 × 1000, where the predicted 10-year CIF (cumulative incidence function) of CVD was estimated from the flexible parametric survival models, which was standardized to the baseline variable (covariates in Model 3 for baseline and mean TyG index, and covariates in Model 4 for TyG index variability)

bCalculated as the difference between the predicted incidence per 1000 population over 10 years across the baseline, mean, and variability of TyG index tertiles