Figure 2.
Mean motor assessment scores and PAC values. (A) Longitudinal changes in motor assessment scores from baseline through 12 weeks of BCI intervention. Each motor assessment tool represented as a separate graph. Y-axis, motor score; X-axis, stages of BCI therapy runs. UEFM, upper extremity Fugl-Meyer; AMAT, Arm Motor Ability Test; MAS, modified Ashworth Scale. (B–D) Theta–, alpha– and beta–gamma PAC values, respectively, across BCI therapy runs. PAC values (mean ± SEM) for each electrode from baseline through 12 weeks of BCI intervention. Y-axis, PAC value; X-axis, stages of BCI therapy runs. Patients were depicted in 17 different colours. Significance levels were based on the pairwise comparisons in ANOVA (N = 17; Bonferroni corrected). *, ** and *** symbols: P ≤ 0.05, 0.01 and 0.001 for Pre-BCI versus earlier, later or final Post-BCI contrasts; # and ### symbols: P ≤ 0.05 and 0.001 for earlier versus later or earlier versus final Post-BCI contrasts; && symbol: P ≤ 0.01 for later versus final Post-BCI contrasts; MI, modulation index; Pre-BCI: before initiating therapy; earlier Post-BCI, 4th week; later Post-BCI, 8th week; final Post-BCI, 12th week.