Table IV.
Thrombotic events and procoagulant markers compared between patients who were Coronavirus disease 2019 (COVID-19) positive during Delta variant wave time (DW) and the rest of the cohort (non-Delta [NDW])
| NDW (n = 206) | DW (n = 50) | P-value | |
|---|---|---|---|
| Venous thrombosis | 155 (75) | 41 (82) | .31 |
| Arterial thrombosis | 85 (41) | 18 (36) | .50 |
| Thrombi location | |||
| Upper extremity | 43 (21) | 11 (22) | .86 |
| Lower extremity | 131 (63) | 33 (66) | .75 |
| Pulmonary embolism | 58 (28) | 14 (28) | .98 |
| Myocardial infarction | 12 (6) | 2 (4) | .61 |
| Aortic thrombi | 3 (1) | 1 (2) | .78 |
| Stroke | 3 (1) | 0 (0) | .39 |
| Multiple thrombotic locationsa | 74 (36) | 16 (32) | .60 |
| Time of thrombosis, daysa | 5 (1-11) | 2 (1-13) | .92 |
| Anticoagulation treatment | 185 (90) | 44 (88) | .71 |
| Start of anticoagulation, daysb | 2 (1-10) | 1 (1-5) | .22 |
| DVT prophylaxis | 134 (65) | 23 (46) | .057 |
| Surgery | 25 (12) | 5 (10) | .67 |
| ICU | 157 (76) | 38 (76) | .97 |
| Deceased | 78 (38) | 21 (42) | .61 |
| D-dimer, μg/mL | 9 (3-2) | 6 (3-13) | .16 |
| Fibrinogen, μg/mL | 384 (280-546) | 355 (150-518) | .29 |
| PT, seconds | 15 (15-17) | 16 (15-18) | .33 |
| aPTT, seconds | 37 (30 – 59) | 50 (35-87) | .008 |
| Ferritin, μg/mL | 794 (412-1365) | 861 (327-1892) | .72 |
DVT, Deep venous thrombosis; ICU, intensive care unit; PT, prothrombin time; aPTT, partial thromboplastin time.
Data are presented as number (%), mean (standard deviation), or median (interquartile range).
a
Time of thrombosis detection in days since hospital admission.
b
Start of anticoagulation treatment in days since hospital admission.