Table 1.

Fitted linear models (y = a + bx) with (w/) and without (w/o) in vivo data for T₁, T₂, T₂*, MD and FA, and differentiated for white matter (top rows), cerebral cortex (middle rows) and deep gray matter (lower rows), respectively

	a (T1 − T2*, MD, FA: ms, mm2/s, a.u.)	b (T1 − T2*, MD, FA: ms/°C, mm2/(s °C), a.u./°C)	R2	p	Δ* [%]	Δ** [%]
White matter
T1
w/ invivo	581.5 ± 35.2	0.0 ± 1.7	− 0.03	0.514	6.6
w/o invivo	566.9 ± 64.9	1.2 ± 4.7	− 0.05	0.637		− 6.6
T2
w/ invivo	105.2 ± 3.3	− 0.5 ± 0.2	0.73	< 0.001	− 1.0
w/o invivo	105.4 ± 5.6	− 0.6 ± 0.4	0.41	0.005		21.6
T2*
w/ invivo	31.7 ± 3.0	0.4 ± 0.1	0.63	< 0.001	− 22.5
w/o invivo	36.1 ± 4.1	0.1 ± 0.3	− 0.06	0.733		− 4.6
MD
w/ invivo	− 4.1E − 05 ± 7.2E − 05	1.6E − 05 ± 3.2E − 06	0.85	< 0.001	− 56.6
w/o invivo	1.0E − 04 ± 4.2E − 05	4.3E − 06 ± 2.9E − 06	0.45	0.003		− 54.3
FA
w/ invivo	3.9E − 01 ± 3.1E − 02	4.63E − 04 ± 1.4E − 03	− 0.02	0.422	− 1.9
w/o invivo	4.0E − 01 ± 2.3E − 02	7.2E − 05 ± 1.0E − 03	− 0.07	0.846		− 0.6
Cerebral cortex
T1
w/ invivo	902.8 ± 73.1	3.8 ± 3.6	0.21	0.024	14.9
w/o invivo	846.4 ± 115.7	8.7 ± 8.4	0.19	0.050		− 24.3
T2
w/ invivo	124.8 ± 10.6	− 0.5 ± 0.5	0.14	0.055	1.9
w/o invivo	124.3 ± 18.7	− 0.5 ± 1.4	0.03	0.252		15.3
T2*
w/ invivo	32.5 ± 3.4	0.3 ± 0.2	0.34	0.004	− 17.4
w/o invivo	35.6 ± 5.5	0.03 ± 0.41	− 0.07	0.838		− 3.1
MD
w/ invivo	− 1.8E − 05 ± 8.2E − 05	2.2E − 05 ± 3.5E − 06	0.87	< 0.001	− 47.4
w/o invivo	1.4E − 04 ± 6.8E − 05	7.7E − 06 ± 5.0E − 06	0.48	0.002		− 58.8
FA
w/ invivo	2.1E − 01 ± 2.4E − 02	− 8.8E − 04 ± 1.3E − 03	0.21	0.023	80.7
w/o invivo	1.8E − 01 ± 2.5E − 02	1.9E − 03 ± 1.8E − 03	0.09	0.143		− 24.3
Deep gray matter
T1
w/ invivo	569.5 ± 36.7	4.6 ± 1.7	0.68	< 0.001	− 2.8
w/o invivo	578.2 ± 61.8	3.9 ± 4.2	0.27	0.023		− 17.6
T2
w/ invivo	90.6 ± 5.6	− 0.2 ± 0.3	0.07	0.137	1.8
w/o invivo	89.6 ± 9.6	− 0.1 ± 0.7	− 0.03	0.475		4.4
T2*
w/ invivo	22.4 ± 3.2	0.4 ± 0.2	0.62	< 0.001	− 24.3
w/o invivo	26.2 ± 4.6	0.11 ± 0.33	− 0.04	0.507		− 11.5
MD
w/ invivo	− 4.8E − 06 ± 4.4E − 05	1.6E − 05 ± 2.8E − 06	0.86	< 0.001	− 49.8
w/o invivo	1.2E − 04 ± 4.8E − 05	5.2E − 06 ± 3.4E − 06	0.40	0.005		− 53.6
FA
w/ invivo	4.3E − 01 ± 4.4E − 02	− 2.6E − 03 ± 2.2E − 03	0.27	0.011	48.7
w/o invivo	3.8E − 01 ± 5.6E − 02	1.8E − 03 ± 3.9E − 03	− 0.03	0.490		− 12.9

95% confidence intervals of the linear fit parameters y-intercept (a) and slope (b) and the adjusted R² value and the p value are shown. The percentage differences between the measured mean in vivo values and the predicted values at 36.5 °C based on the post mortem data (Δ*), taking the measured mean in vivo values as 100% are indicated. The percentage differences between the maximum temperature difference of 4 and 36.5 °C (Δ**) taking the value at 36.5 °C as 100% are listed based on the fit using solely post mortem data