Table 2.

Fitted linear models (y = a + bx) with (w/) and without (w/o) in vivo data for T₁, T₂, T₂*, MD and FA, and differentiated for the additionally investigated deep gray matter subregions

	a (T1 − T2*, MD, FA: ms, mm2/s, a.u.)	b (T1 − T2*, MD, FA: ms/°C, mm2/(s °C), a.u./°C)	R2	p	Δ* [%]	Δ** [%]
Globus pallidus
T1
w/ invivo	524.6 ± 17.3	3.0 ± 0.7	0.78	< 0.001	− 4.7
w/o invivo	539.6 ± 23.2	1.8 ± 1.6	0.32	0.013		− 9.8
T2
w/ invivo	80.7 ± 6.5	− 0.1 ± 0.3	− 0.01	0.379	1.5
w/o invivo	80.4 ± 10.5	− 0.1 ± 0.8	− 0.07	0.786		4.5
T2*
w/ invivo	16.6 ± 3.4	0.4 ± 0.2	0.64	< 0.001	− 32.6
w/o invivo	21.0 ± 4.3	0.1 ± 0.3	− 0.03	0.477		− 8.6
MD
w/ invivo	3.9E − 05 ± 5.5E − 05	1.1E − 05 ± 2.4E − 06	0.80	< 0.001	− 51.5
w/o invivo	1.3E − 04 ± 5.8E − 05	2.5E − 06 ± 4.2E − 06	0.13	0.093		− 36.4
FA
w/ invivo	5.0E − 01 ± 3.6E − 02	− 2.17E − 03 ± 1.7E − 03	0.22	0.021	12.0
w/o invivo	4.8E − 01 ± 3.9E − 02	− 7.1E − 04 ± 2.8E − 03	− 0.06	0.740		5.1
Putamen
T1
w/ invivo	464.8 ± 25.9	9.2 ± 1.2	0.94	< 0.001	− 9.7
w/o invivo	500.6 ± 33.4	6.5 ± 2.1	0.76	< 0.001		− 28.6
T2
w/ invivo	76.6 ± 6.0	0.0 ± 0.4	− 0.05	0.914	− 1.2
w/o invivo	76.7 ± 9.9	0.0 ± 0.8	− 0.05	0.569		1.0
T2*
w/ invivo	18.4 ± 4.1	0.5 ± 0.2	0.53	< 0.001	− 26.7
w/o invivo	22.2 ± 6.0	0.15 ± 0.44	− 0.04	0.548		− 17.3
MD
w/ invivo	4.3E − 06 ± 3.8E − 05	1.5E − 05 ± 1.7E − 06	0.86	< 0.001	− 50.0
w/o invivo	1.2E − 04 ± 5.2E − 05	5.1E − 06 ± 3.7E − 06	0.43	0.003		− 54.1
FA
w/ invivo	4.7E − 01 ± 5.5E − 02	− 5.6E − 03 ± 2.8E − 03	0.53	< 0.001	85.2
w/o invivo	4.0E − 01 ± 3.4E − 02	6.2E − 05 ± 6.4E − 04	0.00	0.868		− 0.5
Caudate nucleus
T1
w/ invivo	535.7 ± 50.8	5.8 ± 2.2	0.69	< 0.001	− 1.0
w/o invivo	539.1 ± 86.4	5.6 ± 5.4	0.29	0.018		− 24.4
T2
w/ invivo	91.8 ± 4.7	− 0.3 ± 0.3	0.29	0.008	− 4.2
w/o invivo	93.1 ± 7.7	− 0.4 ± 0.6	0.13	0.095		17.4
T2*
w/ invivo	25.8 ± 4.1	0.5 ± 0.2	0.52	< 0.001	− 26.1
w/o invivo	30.0 ± 5.9	0.08 ± 0.44	− 0.06	0.663		− 8.0
MD
w/ invivo	− 1.5E − 05 ± 8.3E − 05	1.7E − 05 ± 4.2E − 06	0.85	< 0.001	− 51.8
w/o invivo	1.3E − 04 ± 6.3E − 05	5.0E − 06 ± 4.3E − 06	0.34	0.011		− 52.4
FA
w/ invivo	4.6E − 01 ± 6.0E − 02	− 4.2E − 03 ± 3.1E − 03	0.37	0.003	54.9
w/o invivo	4.1E − 01 ± 4.0E − 02	1.3E − 04 ± 1.7E − 03	− 0.07	0.825		− 1.0
Thalamus
T1
w/ invivo	566.0 ± 52.4	4.4 ± 2.4	0.54	< 0.001	− 5.6
w/o invivo	584.7 ± 90.5	3.0 ± 6.0	0.10	0.119		− 13.9
T2
w/ invivo	101.6 ± 6.3	− 0.4 ± 0.3	0.17	0.039	3.9
w/o invivo	100.2 ± 10.9	− 0.2 ± 0.8	− 0.01	0.373		8.1
T2*
w/ invivo	25.7 ± 3.2	0.4 ± 0.1	0.61	< 0.001	− 21.8
w/o invivo	29.3 ± 4.5	0.11 ± 0.33	− 0.03	0.444		− 10.5
MD
w/ invivo	− 4.0E − 06 ± 5.5E − 05	1.7E − 05 ± 4.1E − 06	0.86	< 0.001	− 47.9
w/o invivo	1.3E − 04 ± 5.5E − 05	5.8E − 06 ± 3.8E − 06	0.38	0.007		− 55.4
FA
w/ invivo	4.0E − 01 ± 5.0E − 02	− 1.1E − 03 ± 2.5E − 03	0.02	0.264	53.3
w/o invivo	3.4E − 01 ± 6.8E − 02	4.0E − 03 ± 4.7E − 03	0.09	0.132		− 26.5

95% confidence intervals of the linear fit parameters y-intercept (a) and slope (b) and the adjusted R² value and the p value are shown. The percentage differences between the measured mean in vivo value and the predicted values at 36.5 °C based on the post mortem data (Δ*), taking the measured mean in vivo values as 100% are indicated. The percentage differences between the maximum temperature difference of 4 and 36.5 °C (Δ**) taking the value at 36.5 °C as 100% are listed based on the fit using solely post mortem data