Fig. 3.

Arithmetic mean (± SD) concentrations of trofinetide in a whole blood, b whole blood (log scale), and c urine following administration of a single oral dose of trofinetide in the morning fasted (treatment A: reference), fed (treatment B: test), and evening fasted (treatment C: test [whole blood only]) states: Pharmacokinetic analysis set. A fasted in the morning (reference; morning fasted state), B fed in the morning with a high-fat meal (test; morning fed state), C fasted in the evening (test; evening fasted state), h hours, SD standard deviation