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. Author manuscript; available in PMC: 2023 Feb 17.
Published in final edited form as: Mutat Res Rev Mutat Res. 2022 Feb 17;789:108413. doi: 10.1016/j.mrrev.2022.108413

Figure 5: Model Systems to Research Circadian Disruption.

Figure 5:

Genetic models of clock gene disruption are displayed on the left, with representations of the most common core clock gene mutations. Environmental clock disruptions are shown on the right, with schematics of the most frequently utilized light schedules to induce circadian dysregulation. Lights-on is represented by the yellow boxes and lights-off with black boxes.