Table 1.

Carcinogens classified as Group 1 in IARC Monographs Volume 100F-118 that were included in the systematic literature review.

Group 1 Carcinogen	Most recent Monograph Number	Evidence of Genotoxicity: Animals	Evidence of Genotoxicity: Humans	Epigenetic data in last monograph	Epigenetic data in this review
1,3-Butadiene	100F	Yes	Yes	Yes	Yes
4,4′-Methylenebis (2-Chlorobensenamine)	100F	Yes	Yes	Yes	Yes
4-Aminobiphenyl	100F	Yes	Yes	Yes	Yes
Aflatoxins (naturally occurring mixtures)	100F	Yes	Yes	Yes	Yes
Benzene	100F	Yes	Yes	Yes	Yes
Benzidine	100F	Yes	Yes	Yes	Yes
Benzo[a]pyrene	100F	Yes	Yes	Yes	Yes
Coal tar pitch	100F	Yes	Yes	No	Yes
Coke production, occupational exposure	100F	Yes	Yes	Yes	Yes
Engine exhaust, diesel	105	Yes	Yes	No	Yes
Formaldehyde	100F	Yes	Yes	Yes	Yes
Lindane	113	Yes	Yes	No	Yes
Occupational exposure as a painter	100F	No	Yes	No	Yes
Outdoor air pollution	109	Yes	Yes	Yes	Yes
Pentachlorophenol	117	No	Yes	Yes	Yes
Polychlorinated biphenyls	107	Yes	Yes	Yes	Yes
Polychlorinated biphenyls, dioxin-like	107	Yes	Yes	Yes	Yes
Sulfur mustard	100F	Yes	Yes	Yes	Yes
Trichloroethylene	106	Yes	Yes	Yes	Yes
Vinyl chloride	100F	Yes	Yes	Yes	Yes
Welding fumes	118	Yes	Yes	Yes	Yes
1,2-Dichloropropane	110	Yes	Yes	No	No
2-Napthylamine	100F	Yes	Yes	No	No
Bis(chloromethyl)ether and chloromethyl methyl ether	100F	No	Yes	No	No
Coal gasification	100F	Yes	No	No	No
Ethylene oxide	100F	Yes	Yes	No	No
Isopropyl alcohol manufacture by the strong-acid process	100F	No	Yes	No	No
Mineral oils, untreated or mildly treated	100F	No	Yes	No	No
Mists from strong inorganic acids	100F	No	Yes	No	No
Occupation exposures during coal-tar distillation	100F	Yes	Yes	No	No
Occupational exposure during aluminum production	100F	No	Yes	No	No
Occupational exposures during iron and steel founding	100F	No	Yes	No	No
Occupational exposures in the rubber manufacturing industry	100F	No	Yes	No	No
Ortho-toluidine	100F	Yes	Yes	No	No
Shale oils	100F	Yes	No	No	No
Soot, as found in the occupation exposure of chimney-sweeps	100F	No	Yes	No	No