Cvietusa 2012.

Study characteristics
Methods	Design: randomised controlled trial Duration: 1 year follow‐up Setting: children with persistent asthma
Participants	Population: total 1393 children: 290 in the intervention group vs 303 in the control group Age: 3 to 12 years old
Interventions	Intervention: received up to 3 tailored speech recognition reminder calls when they were due to refill their ICS. The calls provided information about asthma, facilitated a rapid ICS refill, and offered an opportunity to receive a call back from an asthma nurse specialist Control: usual care (no reminders)
Outcomes	Time to first ICS refill; proportion of days with medication on hand
Notes	Type of publication: abstract only
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomisation occurred but no detail given on how
Allocation concealment (selection bias)	Unclear risk	No allocation concealment described
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Blinding unlikely to have been achieved but unlikely to have affected ICS refill
Blinding of outcome assessment (detection bias) All outcomes	Low risk	No blinding of outcome assessors described; adherence monitored by prescription refill so unlikely affected by knowledge of intervention group
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	No loss of follow‐up data reported
Selective reporting (reporting bias)	Unclear risk	Methods did not describe what outcomes were planned