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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Oct 9;1867(1):159067. doi: 10.1016/j.bbalip.2021.159067

Figure 3. Enzyme activity of PLA2s toward sn-1 vinyl ether phospholipids and diester phospholipids.

Figure 3.

The activity of (A) GIVA cPLA2, (B) GVIA iPLA2, and (C) GV sPLA2 is shown toward sn-1 vinyl ether or ester C18 sn-2 X PC, where X is 18:1, 20:4, or 22:6. (D) The activity of GIVA cPLA2 toward sn-1 vinyl ether or ester C18 sn-2 20:4 PC in equal proportions with 100 µM total phospholipid. The activity of (E) GVIA iPLA2 and (F) GV sPLA2 toward sn-1 vinyl ether or ester C18 sn-2 18:1 PC in equal proportions with 100 µM total phospholipid. The amount of lyso products were determined and quantified using authentic LPC primary and internal standards. Error bars show SD. Asterisks indicate statistical significance. **P < 0.01.