Table 7.
Multivariable Cox regression analysis for overall survival (n = 139).
| Variables | Univariate Analysis |
Multivariate Analysis |
||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Lenvatinib plus sintilimab treatment | 0.35 (0.20–0.62) | 0.005 | 0.35 (0.16–0.78) | 0.010 |
| Child-pugh class (A) | 0.74 (0.40–1.37) | 0.297 | ||
| PS score (≤1′) | 0.88 (0.43–1.79) | 0.708 | ||
| AFP (≥400 μg/L) | 1.48 (0.88–2.51) | 0.133 | 2.96 (1.34–6.58) | 0.118 |
| Albumin (<35 g/L) | 1.45 (0.86–2.50) | 0.156 | 2.96 (1.34–6.58) | 0.187 |
| TBIL (<20.5 μmol/L) | 0.73 (0.41–1.30) | 0.286 | ||
| GGT (≥33 U/L) | 1.50 (0.68–3.49) | 0.304 | ||
| PTA (<75%) | 1.20 (0.72–2.12) | 0.423 | ||
| PLT (<100∗109/L) | 0.88 (0.50–1.54) | 0.650 | ||
| BCLC stage (C) | 0.37 (0.21–0.64) | 0.003 | 2.73 (1.32–5.61) | 0.006 |
Hazard ratio (HR); Confidence interval (CI); Performance status (PS); Barcelona Clinic Liver Cancer (BCLC); Total bilirubin (TBIL); Prothrombin time activity (PTA); Alpha fetoprotein (AFP); Gamma-glutamyl transpeptidase (GGT); Platelets (PLT).