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. 2022 May 23;25(6):104440. doi: 10.1016/j.isci.2022.104440

Figure 1.

Figure 1

IL-3 induction is associated with ameliorated asthma in children

(A) ELISA analysis of IL-3 levels in the supernatant from peripheral blood mononuclear cells (PBMCs) isolated from healthy control and asthmatic children and cultured with PHA for 24h (n = 19/21).

(B) Correlation between the IL-3 quantified by ELISA analysis in the supernatant from PHA-stimulated PBMCs isolated from healthy control (n = 18: IL-3 n = 20; FEV1% predicted n = 19) and asthmatic children and the predicted FEV1%, predicted (FEV1% predicted n = 23; IL-3: n = 20; correlation FEV1% predicted and IL-3: n = 20).

(C) the PEF% predicted (n = 20; IL-3 n = 20 and PEF% n = 23) at the baseline visit. Data are presented as means ± SEMs. Two-tailed Student’s t test was used to calculate statistical significance. ∗p ≤ 0.05; ∗∗p ≤ 0.01, ∗∗∗p ≤ 0.001, ∗∗∗∗p ≤ 0.0001. For the Correlations, the Pearson coefficient was used after data normalization.