Table 5.

Advantages and disadvantages of the 5 imaging softwares used in the present study

Name	Vantages	Disadvantages
ITK-Snap	Free source	Not user-friendly interface
	Good threshold sensitivity	Designed for usage in medicine
	Tools for checking and correction of segmentation mask in 2D views
	Compatibility with multiple operating systems (Windows, Mac OS X, Linux)
Slicer 3D	Free source	Not user-friendly interface
	Good threshold sensitivity	Lack of 2D correction tools for segmentation mask
	Compatibility with multiple operating systems (Windows, Mac OS X, Linux)
Dolphin 3D	User-friendly interface	Not free source
	Designed for orthodontists and maxillofacial surgeons	In regions with complex morphology (ethmoid cells) the segmentation algorithm does not distinguish thin osseous laminae from air
	Good threshold sensitivity	Compatibility with single operating system (Windows)
Invesalius	Free source	Not user-friendly interface
	Good threshold sensitivity
	Compatibility with multiple operating systems (Windows, Mac OS X, Linux)
Seg3D	Free source	Not user-friendly interface
	Tools for checking and correction of segmentation mask in 2D views	Deficient threshold sensitivity
		Compatibility with single operating system (Windows)