Figure 2.

Transgenic prostacyclin does not require Fzd₉ expression for preventive effects in the mouse lung

(A) Change in weights of mice in the urethane model.

(B) Average adenoma number per mouse in the urethane exposed groups.

(C) Diameter of adenomas in urethane exposed groups. WT, wild type; Pgis^Tg, prostacyclin synthase transgenic; Pgis^Tg x Fzd₉^−/− prostacyclin synthase transgenic with Fzd₉ knockout. Data are represented as mean ± SEM. A one-way ANOVA with Tukey’s post-hoc test was used to measure significance. ∗p < 0.05.