Figure 4.

Optogenetic activation of ALA during motion bouts promotes transitions to sleep bouts

(A) Schematic of the experiment. Blue light stimulation was applied for 3 s upon transition to a motion bout.

(B) Comparison of the latency to MS transitions following light stimulation. p-value in Mann-Whitney’s U test is indicated.

(C) Comparison of the cumulative distribution of the latency to MS transitions following light stimulation. p-value in the Kolmogorov-Smirnov test is indicated.

(D–G) Comparison of the pattern of locomotor activity around the light stimulation (D, F) and the averaged locomotor activity during the 5 s after light stimulation (E and G) between ATR+ and ATR− worms in lethargus. Shaded areas indicate ±SEM. p-values in unpaired t test are indicated. N and n in the figure represent numbers of animals and trials, respectively.