Table 2. Outcomes of receiver operating characteristic curves and Youden index for 5 candidate miRNAs and the three-miRNA panel.
| Variables | AUC | P value | 95% CI | Associated criterion | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| miR-106a-5p | 0.634 | 0.0025 | 0.555 to 0.707 | ≤1 | 73.17 | 53.66 |
| miR-145-5p | 0.677 | <0.001 | 0.600 to 0.748 | ≤0.98 | 75.61 | 56.10 |
| miR-132-3p | 0.781 | <0.001 | 0.710 to 0.842 | ≤0.83 | 68.29 | 81.71 |
| miR-7-5p | 0.778 | <0.001 | 0.707 to 0.839 | ≤0.76 | 59.76 | 84.15 |
| miR-148b-3p | 0.837 | <0.001 | 0.771 to 0.890 | >1.1 | 81.71 | 71.95 |
| Three-miRNA panel | 0.922 | <0.001 | 0.870 to 0.958 | >0.42286 | 90.24 | 81.71 |
miRNA, microRNA; AUC, area under curve; CI, confidence interval.