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Immunological parameters (cytokines and immunoglobulin) in different experimental groups. arepresents significance compared with the corresponding healthy control group I and brepresents significance compared with the corresponding diabetic group III (P < 0.05). Group I: healthy control rats, group II: melatonin administrated control rats, group III: non-treated STZ diabetic rats and group IV: melatonin treated STZ diabetic rats.
