Table 5. Crude mortality rates and hazard ratios for CVD mortality according to non-fasting triglyceride category stratified by age <65 and ≥65 years.
| Baseline non-fasting triglyceride level | |||||||
| ≤59 mg/dL | 60–89 mg/dL | 90–119 mg/dL | 120–149 mg/dL | 150–179 mg/dL | 180–209 mg/dL | ≥210 mg/dL | |
| CVD death | |||||||
| Age <65 years | |||||||
| Men | |||||||
| Number of participants | 176 | 432 | 468 | 311 | 249 | 172 | 430 |
| Person-years | 3,238 | 8,080 | 8,824 | 5,864 | 4,671 | 3,239 | 8,085 |
| Number of deaths | 8 | 19 | 20 | 10 | 5 | 3 | 24 |
| Crude mortality rate | 2.5 | 2.4 | 2.3 | 1.7 | 1.1 | 0.9 | 3 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 2.13 (0.69–6.51) | 2.02 (0.75–5.41) | 1.88 (0.70–5.01) | 1.56 (0.53–4.59) | Ref. | 0.91 (0.21–3.83) | 2.93 (1.11–7.68) |
| Model 2 | 1.86 (0.57–6.08) | 2.00 (0.73–5.51) | 1.71 (0.63–4.63) | 1.45 (0.49–4.29) | Ref. | 0.85 (0.20–3.59) | 2.57 (0.97–6.82) |
| Model 3 | 1.68 (0.49–5.79) | 1.88 (0.67–5.29) | 1.63 (0.59–4.48) | 1.42 (0.48–4.21) | Ref. | 0.85 (0.20–3.57) | 2.65 (0.99–7.07) |
| Women | |||||||
| Number of participants | 571 | 888 | 634 | 434 | 241 | 145 | 269 |
| Person-years | 11,176 | 17,310 | 12,287 | 8,386 | 4,657 | 2,770 | 5,180 |
| Number of deaths | 5 | 12 | 13 | 6 | 6 | 5 | 10 |
| Crude mortality rate | 0.4 | 0.7 | 1.1 | 0.7 | 1.3 | 1.8 | 1.9 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 0.81 (0.24–2.70) | 0.93 (0.34–2.50) | 1.10 (0.42–2.91) | 0.56 (0.18–1.74) | Ref. | 1.39 (0.42–4.57) | 1.42 (0.51–3.91) |
| Model 2 | 1.09 (0.31–3.78) | 1.17 (0.42–3.20) | 1.20 (0.45–3.20) | 0.54 (0.17–1.69) | Ref. | 1.45 (0.44–4.78) | 1.17 (0.42–3.28) |
| Model 3 | 1.00 (0.26–3.72) | 1.09 (0.38–3.15) | 1.15 (0.42–3.13) | 0.52 (0.16–1.66) | Ref. | 1.46 (0.44–4.81) | 1.21 (0.42–3.45) |
| Total | |||||||
| Number of participants | 747 | 1,320 | 1,102 | 745 | 490 | 317 | 699 |
| Person-years | 14,414 | 25,390 | 21,111 | 14,250 | 9,328 | 6,009 | 13,265 |
| Number of deaths | 13 | 31 | 33 | 16 | 11 | 8 | 34 |
| Crude mortality rate | 0.9 | 1.2 | 1.6 | 1.1 | 1.2 | 1.3 | 2.6 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 1.32 (0.59–2.96) | 1.38 (0.69–2.75) | 1.42 (0.72–2.82) | 0.99 (0.46–2.14) | Ref. | 1.16 (0.46–2.88) | 2.13 (1.08–4.21) |
| Model 2 | 1.43 (0.61–3.33) | 1.56 (0.76–3.16) | 1.42 (0.71–2.83) | 0.93 (0.43–2.02) | Ref. | 1.09 (0.44–2.74) | 1.83 (0.91–3.65) |
| Model 3 | 1.29 (0.53–3.15) | 1.46 (0.70–3.03) | 1.35 (0.67–2.74) | 0.91 (0.42–1.97) | Ref. | 1.10 (0.44–2.74) | 1.89 (0.94–3.80) |
| Age ≥65 years | |||||||
| Men | |||||||
| Number of participants | 78 | 155 | 127 | 87 | 46 | 41 | 81 |
| Person-years | 855 | 1,847 | 1,588 | 1,169 | 655 | 507 | 1,128 |
| Number of deaths | 16 | 33 | 27 | 16 | 4 | 13 | 16 |
| Crude mortality rate | 18.7 | 17.9 | 17.0 | 13.7 | 6.1 | 25.6 | 14.2 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 2.70 (0.90–8.11) | 2.29 (0.80–6.50) | 2.43 (0.85–6.97) | 1.97 (0.65–5.91) | Ref. | 3.25 (1.05–10.02) | 2.07 (0.69–6.22) |
| Model 2 | 3.22 (1.02–10.12) | 2.53 (0.86–7.40) | 2.48 (0.85–7.22) | 1.89 (0.62–5.72) | Ref. | 3.17 (1.02–9.82) | 2.07 (0.68–6.28) |
| Model 3 | 4.52 (1.40–14.60) | 3.37 (1.13–10.06) | 3.02 (1.03–8.87) | 2.15 (0.71–6.51) | Ref. | 3.17 (1.02–9.79) | 1.83 (0.60–5.59) |
| Women | |||||||
| Number of participants | 53 | 166 | 198 | 116 | 95 | 65 | 103 |
| Person-years | 634 | 2,336 | 2,793 | 1,720 | 1,444 | 1,074 | 1,667 |
| Number of deaths | 17 | 37 | 41 | 25 | 16 | 8 | 18 |
| Crude mortality rate | 26.8 | 15.8 | 14.7 | 14.5 | 11.1 | 7.4 | 10.8 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 2.28 (1.15–4.53) | 1.33 (0.73–2.39) | 1.36 (0.76–2.42) | 1.31 (0.70–2.46) | Ref. | 0.68 (0.29–1.59) | 1.05 (0.53–2.07) |
| Model 2 | 1.97 (0.96–4.05) | 1.24 (0.68–2.27) | 1.35 (0.75–2.43) | 1.29 (0.68–2.43) | Ref. | 0.61 (0.26–1.45) | 1.10 (0.56–2.18) |
| Model 3 | 2.06 (0.98–4.32) | 1.30 (0.70–2.42) | 1.38 (0.76–2.51) | 1.30 (0.69–2.46) | Ref. | 0.61 (0.25–1.43) | 1.06 (0.52–2.12) |
| Total | |||||||
| Number of participants | 131 | 321 | 325 | 203 | 141 | 106 | 184 |
| Person-years | 1,488 | 4,182 | 4,381 | 2,889 | 2,099 | 1,581 | 2,794 |
| Number of deaths | 33 | 70 | 68 | 41 | 20 | 21 | 34 |
| Crude mortality rate | 22.2 | 16.7 | 15.5 | 14.2 | 9.5 | 13.3 | 12.2 |
| Hazard ratio (95% CI) | |||||||
| Model 1 | 2.16 (1.23–3.79) | 1.52 (0.92–2.50) | 1.58 (0.96–2.61) | 1.43 (0.83–2.44) | Ref. | 1.30 (0.70–2.40) | 1.29 (0.74–2.24) |
| Model 2 | 2.13 (1.18–3.84) | 1.49 (0.89–2.50) | 1.58 (0.95–2.62) | 1.42 (0.83–2.43) | Ref. | 1.21 (0.65–2.24) | 1.35 (0.77–2.35) |
| Model 3 | 2.39 (1.31–4.38) | 1.66 (0.98–2.81) | 1.69 (1.01–2.82) | 1.47 (0.86–2.53) | Ref. | 1.19 (0.64–2.21) | 1.25 (0.71–2.20) |
CI, confidence interval; CVD, cardiovascular disease.
Model 1 was adjusted for age.
Model 2 was adjusted for variables in model 1 plus body mass index, total cholesterol, hypertension, diabetes, smoking status, and alcohol drinking status.
Model 3 was adjusted for variables in model 2 plus high-density lipoprotein cholesterol.
The model for total participants (in which the sexes were combined) was also adjusted for sex.
Crude mortality rate is shown as per 1,000 person-years.