Table 2.
Univariable and multivariable Cox analysis of CAPN2 expression for OS.
| Variables | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P-value | HR | 95%CI | P-value | |
| Age (years) | ||||||
| ≥60 | 1.188 | 0.662–2.133 | 0.563 | |||
| <60 | Ref. | - | - | |||
| Gender | ||||||
| Male | 1.477 | 0.811–2.688 | 0.202 | |||
| Female | Ref. | - | - | |||
| Histologic grade | ||||||
| G1+G2 | Ref. | - | - | |||
| G3+G4 | 3.758 | 2.004–7.048 | <0.001 | 2.888 | 1.338–6.234 | 0.007 |
| T stage | ||||||
| T1+T2 | Ref. | - | - | |||
| T3+T4 | 1.649 | 0.792–3.434 | 0.182 | |||
| N stage | ||||||
| N0+NX | Ref. | - | - | |||
| N1 | 1.594 | 0.864–2.941 | 0.136 | |||
| M stage | ||||||
| M0+MX | Ref. | - | - | - | - | - |
| M1 | 3.314 | 1.141–9.632 | 0.028 | 1.703 | 0.452–6.413 | 0.431 |
| AJCC stage | ||||||
| I+II | Ref. | - | - | - | - | - |
| III+IV | 3.447 | 1.178–10.032 | 0.024 | |||
| CAPN2 expression | ||||||
| Low | Ref. | - | - | - | - | - |
| High | 0.445 | 0.245–0.809 | 0.008 | 0.583 | 0.283–1.202 | 0.144 |