Table 3.
Univariate analysis of perioperative clinical data of patients in the PVST group and non-PVST group.a
| Items | PVST group (n = 132) | Non-PVST group (n = 105) | t/z/χ 2 | P |
|---|---|---|---|---|
| Gender [F/M, n (%)] | 67(50.8)/65(49.2) | 56(53.3)/49(46.7) | 0.155 | 0.693 |
| Age (year) | 29.00 (22.00 37.00) | 26.00(20.00 32.00) | −1.684 | 0.092 |
| Child-Pugh [A/B, n (%)] | 68(51.5)/64(48.5) | 66(62.9)/39(37.1) | 3.062 | 0.080 |
| Method of operation [n (%)] | 0.001 | 0.974 | ||
| Splenectomy | 118(89.4) | 94(89.5) | ||
| SPD | 14(10.6) | 11(10.5) | ||
| Anatomical splenectomy [yes/no, n (%)] | 56(42.4)/76(57.6) | 49(46.7)/56(53.3) | 0.427 | 0.514 |
| BMI (kg/m2) | 23.51 ± 2.56 | 23.54 ± 1.87 | −0.107 | 0.915 |
| Diabetes [yes/no, n (%)] | 28(21.2)/104(78.8) | 19(18.1)/86(81.9) | 0.357 | 0.550 |
| Hypertension [yes/no, n (%)] | 24(18.2)/108(81.8) | 16(15.2)/89(84.8) | 0.361 | 0.548 |
| Ascites [yes/no, n (%)] | 49(37.1)/83(62.9) | 33(31.4)/72(68.6) | 0.838 | 0.360 |
| ALB (g/L) | 37.74 ± 4.49 | 37.95 ± 4.83 | −0.355 | 0.723 |
| AST (U/L) | 34.92 ± 8.28 | 34.38 ± 5.03 | 0.623 | 0.534 |
| ALT (U/L) | 28.00(20.00 37.00) | 28.00(19.50 38.00) | −0.180 | 0.857 |
| WBC (×109/L) | 2.67 ± 0.87 | 2.63 ± 0.81 | 0.357 | 0.721 |
| HB (g/L) | 107.23 ± 11.55 | 107.73 ± 8.17 | −0.389 | 0.698 |
| FIB (g/L) | 1.66 ± 0.26 | 1.69 ± 0.18 | −1.038 | 0.300 |
| TBIL (µmmol/L) | 27.72 ± 5.00 | 27.12 ± 4.9 | 0.926 | 0.356 |
| APTT (s) | 43.25(36.80 48.95) | 40.60(36.95 46.00) | −1.103 | 0.270 |
| PT (s) | 14.92 ± 1.96 | 14.64 ± 1.42 | 1.285 | 0.200 |
| INR | 1.35 ± 0.15 | 1.34 ± 0.14 | 0.529 | 0.597 |
| PLT (×109/L) | ||||
| Before | 58.16 ± 7.02 | 57.39 ± 9.16 | 0.709 | 0.479 |
| POD1 | 140.89 ± 10.84 | 141.90 ± 31.60 | −0.310 | 0.757 |
| POD3 | 224.95 ± 17.27 | 218.64 ± 11.45 | 3.369 | 0.001 |
| POD7 | 487.17 ± 35.40 | 441.07 ± 30.61 | −10.567 | <0.001 |
| POD14 | 567.64 ± 24.58 | 559.87 ± 41.30 | 1.704 | 0.090 |
| POD21 | 446.55 ± 44.04 | 446.85 ± 65.00 | −0.040 | 0.968 |
| D-D (mg/L) | ||||
| Before | 0.66 ± 0.15 | 0.64 ± 0.17 | 0.990 | 0.323 |
| POD1 | 5.63 ± 0.39 | 5.59 ± 1.39 | 0.273 | 0.785 |
| POD3 | 9.36 ± 1.21 | 9.35 ± 1.63 | 0.079 | 0.937 |
| POD7 | 14.52 ± 1.58 | 13.98 ± 1.02 | −3.137 | 0.002 |
| POD14 | 17.21 ± 1.67 | 15.24 ± 1.99 | 8.276 | <0.001 |
| POD21 | 12.46 ± 2.01 | 12.32 ± 1.64 | 0.589 | 0.556 |
| The time of operation (min) | 213.09 ± 6.92 | 214.57 ± 7.60 | −1.565 | 0.119 |
| Intraoperative bleed loss (mL) | 221.01 ± 8.37 | 220.00 ± 8.15 | 0.932 | 0.352 |
| Portal vein diameter (mm) | 15.73 ± 1.64 | 14.01 ± 2.11 | −6.878 | <0.001 |
| Portal vein velocity (cm/s) | 22.27 ± 1.55 | 23.18 ± 1.16 | 4.856 | <0.001 |
| portal vein flow (ml/min) | 897.73 ± 41.46 | 919.38 ± 26.83 | −5.189 | <0.001 |
| Splenic vein diameter (mm) | 10.89 ± 2.02 | 9.01 ± 1.95 | 7.173 | <0.001 |
a
Data are indicated as mean ± standard deviation, median (interquartile range) values, or the ratio of patients.
PVST, portal vein system thrombosis; SPD, splenectomy with portal devascularization; Before, preoperative day; POD, postoperative day; BMI, body mass index; ALB, albumin; AST, aspartate transaminase; ALT, alanine transaminase; TBIL, total bilirubin; WBC, white blood cell; HB, hemoglobin; APTT, activated partial thromboplastin time; PT, prothrombin time; INR, international standardized ratio; FIB, fibrinogen; PLT, perioperative platelet count; D-D, D-dimer.